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The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the advantage of the drug outweighs the risk of a possible rise in blood pressure. Using two separate drugs to shed weight can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight loss and the people that go through it one should err along the side of caution and let the FDA do its job and demand some research be done so your public recognizes the side effects and perils associated with the medications before we take them. Keep in mind that drug companies will be in business to generate money and that they would say anything to keep people on the medications. Researchers found that participants investing in this drug for any year, dropped a few pounds within a month and have kept the body weight off throughout the 56 weeks with the study. Contrave is a combination of the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs that are made up of more than one active ingredient, which might make them more potent and safer. Combo-pilling is the newest fad or also the newest in the future under scrutiny and so it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular may be the fact that since right now there are not any long term prescription slimming capsules that have been authorized by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be licensed by the FDA. Seizures are a side effect with Contrave and really should not be taken in individuals with seizure disorders. The drug could also raise blood pressure and heartrate, and mustn't be used in people who have a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise hypertension and heartrate and must 't be used in patients with uncontrolled high blood pressure levels, as well as by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients with a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. 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